General Articles Oral Pathology

Hand Foot Mouth disease

Hand Foot Mouth disease

Etiology

• A very common cause of hand foot mouth disease is enterovirus infection (coxsackievirus A10 or A16), which may occur in mild epidemic proportion, chiefly in children
• Incubation period is short, usually less than 1 week

Clinical Presentation

• Oral mucosal lesions with focal herpes simplex–like appearance, usually involving nonkeratinized tissue (soft palate, floor of mouth, labial-buccal mucosa)
• Accompanying palmar, plantar, and digital lesions are deeply seated, vesicular, and erythematous
• Short course with mild symptoms

Diagnosis

• Concomitant oral and cutaneous lesions
• Skin lesions commonly involve hands and feet.
• Skin lesions may involve buttocks.
• Antibody-titer increase measured between acute and recovery phases

Differential Diagnosis

• Herpangina
• Herpes simplex infection
• Acute lymphonodular pharyngitis

Treatment

• Symptomatic treatment only
• Patient should be cautioned against the use of aspirin to manage fever.

Prognosis

• Excellent
• Lifelong immunity, but it is strain specific

Pictures

Hand Foot Mouth disease

Hand Foot Mouth disease

Hand Foot Mouth disease

Hand Foot Mouth disease

Hand Foot Mouth disease

Hand Foot Mouth disease