Free Medical Books Immunology

Regulation of Cytokine Gene Expression in Immunity and Diseases


Regulation of Cytokine Gene Expression in Immunity and Diseases PDF

Regulation of Cytokine Gene Expression in Immunity and Diseases
Author Xiaojing Ma
Isbn 940240919X
File size 5.2 MB
Year 2016
Pages 225
Language English
File format PDF
Category Free Medical Books,Immunology
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Book Description:

This book explores the major cytokines, such as IL-1 and IFN-γ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.

 


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