Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy PDF
|File size||6.58 MB|
|Category||Free Medical Books,Oncology|
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This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.