Free Medical Books Oncology

Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy


Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy PDF

Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
Author Emmanuel Donnadieu
Isbn B01LAE27V4
File size 6.58 MB
Year 2016
Pages 199
Language English
File format PDF
Category Free Medical Books,Oncology
Download the Book

Book Description:

This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.

The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.


About the author

Dr.Jack

I’m a Doctor.
Collecting Free Medical Books is my Favorite.
If you think that this Website helped you please ‬((Share It))
Thanks a lot