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Huntington’s Disease

Huntington’s Disease: Etiology and Symptoms Diagnosis and Treatment PDF

Huntington’s Disease
Author Thomas J. Visser
Isbn 1617287490
File size 3.61 MB
Year 2010
Pages 254
Language English
File format PDF
Category Free Medical Books
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Book Description:

Huntington’s disease, chorea or disorder (HD) is an incurable neurodegenerative genetic disorder, which affects muscle coordination and some cognitive functions, typically becoming noticeable in middle age. It is the most common genetic cause of abnormal involuntary writhing movements called chorea and is much more common in people of Western European descent than in those from Asia or Africa. The disease is caused by a dominant mutation on either of the two copies of a gene called Huntington. This book gathers and presents current research in the study of Huntington’s Disease including the outlining effects of mutant htt in the nucleus and cytoplasm and the role of cell-cell interactions in Huntington’s Disease pathology, as well as a review of the role of Huntington (HTT) interacting proteins.

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