Free Medical Books Oncology

Molecular Oncology


Molecular Oncology: Causes of Cancer and Targets for Treatment PDF

Molecular Oncology
Author Edward P. Gelmann
Isbn 0521876621
File size 39.07 MB
Year 2014
Pages 979
Language English
File format PDF
Category Free Medical Books,Oncology
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Book Description:

The genomic era has allowed enormous strides in our understanding of the molecular changes that underlie malignant transformation. Mutations have been discovered that are critical drivers of large cross-sections of human cancers. These discoveries have allowed us to find drugs that target these drivers and make important strides in treatment. Genomics and high-throughput technologies have illuminated the complexity of cancer and the facility with which cancers adapt during their natural history. The field is evolving rapidly with new discoveries and new drugs reported monthly. This book is a timely foundation for understanding in context the origins of molecular oncology and its future directions. The content reviews available technologies for the analysis of cancer tissues and genes; summaries of key oncogenic pathways from a molecular perspective; the technologies, pathways and targeted therapies of a wide range of human malignancies; and new pharmacologic therapies that have a common mechanistic target.


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