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Translating Molecules into Medicines

Translating Molecules into Medicines PDF: Cross-Functional Integration at the Drug Discovery-Development Interface

Translating Molecules into Medicines PDF
Author Shobha N. Bhattachar
File size 9.36 MB
Year 2017
Pages 461
Language English
File format PDF
Category
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Book Description

Tackling translational medicine with a focus on the drug discovery development-interface this book integrates approaches and tactics from multiple disciplines rather than just the pharmaceutical aspect of the field. The authors of each chapter address the paradox between the molecular understanding of diseases drug discovery and drug development. Laying out the detailed trends from various fields different chapters are dedicated to target engagement toxicological safety assessments and the compelling relationship of optimizing early clinical studies with design strategies. The book also highlights the importance of balancing the three pillars: sufficient efficacy acceptable safety and appropriate pharmacokinetics all of which are crucial to successful efforts in discovery and development. With discussions regarding the combined approaches of molecular research personalized medicine pre-clinical and clinical development as well as targeted therapies―this compendium is a flexible fit perfect for professionals in the pharmaceutical industry and related academic fields.

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