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Cardiovascular Diseases PDF

Cardiovascular Diseases PDF Free Download

Cardiovascular Diseases PDF Free Download

Preface:

Cardiovascular diseases remain the leading cause of death globally, though the mortality associated with these diseases in developed countries has been significantly reduced over the past decades owing to the availability of effective treatment approaches. Among the available therapeutic strategies, drug therapy continues to be an important modality in the management of various forms of cardiovascular diseases. In this context, cardiovascular pharmacology serves as the foundation for pharmacotherapeutics of cardiovascular diseases and has become an increasingly important subject in cardiovascular medicine. While there are multiple excellent pharmacology books with chapters being devoted to cardiovascular drugs, a book that systematically integrates essentials, advancements, and clinical correlations for cardiovascular drugs would facilitate the learning of knowledge on using these pharmacological agents to prevent and treat cardiovascular diseases. The aim of this book is to provide a comprehensive coverage of molecular pharmacology of various classes of cardiovascular drugs and evidence‐based pharmacotherapeutics in the management of common cardiovascular diseases and conditions, including dyslipidemias, hypertension, ischemic heart disease, heart failure, cardiac arrhythmias, and ischemic stroke.As outlined in the following text, the book contains eight units with a total of 28 chapters. Unit I (Chapters 1 and 2): General Introduction Unit II (Chapters 3–5): Dyslipidemias Unit III (Chapters 6–12): Hypertension and Multitasking Cardiovascular Drugs Unit IV (Chapters 13–15): Ischemic Heart Disease: Stable Ischemic Heart Disease Unit V (Chapters 16–19): Ischemic Heart Disease: Acute Coronary Syndromes Unit VI (Chapters 20–22): Heart Failure Unit VII (Chapters 23–25): Cardiac Arrhythmias Unit VIII (Chapters 26–28): Ischemic Stroke To set the stage for subsequently discussing the diverse topics of cardiovascular pharmacology and therapeutics, Unit I provides two introductory chapters. Chapter 1 introduces general aspects of cardiovascular diseases, including definition, classification, and epidemiology, as well as the overall strategies for prevention and control. Chapter 2 briefly surveys the general principles of pharmacology and provides an overview of the key and emerging concepts in cardiovascular pharmacology and therapeutics. Unit II consists of three chapters (Chapters 3–5) devoted to the discussion of pharmacology and therapeutics of dyslipidemias. Chapter 3 reviews lipoprotein metabolism and lipoprotein disorders to lay a basis for understanding how drugs impact diverse lipoprotein metabolic pathways to treat various dyslipidemias. Chapter 4 examines molecular
�pharmacology of various classes of drugs for treating dyslipidemias, including statins, bile acid sequestrants, cholesterol absorption inhibitors, fibrates, niacin, as well as newly approved drugs for homozygous familial hypercholesterolemia. The chapter also considers phytosterols, phytostanols, omega‐3 fatty acids, and emerging drugs for dyslipidemias. The principles and current evidence‐based guidelines for management of dyslipidemias in clinical practice are covered in Chapter 5. Unit III consisting of seven chapters (Chapters 6–12)
�discusses pharmacology and therapeutics of hypertension, as well as various classes of cardiovascular drugs. Chapter 6
�provides an overview of hypertension, including definition, epidemiology, and pathophysiology and drug targeting. Because the different drug classes used for treating
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