The past 50 years have witnessed remarkable achievements in the treatment and prevention of coronary artery disease, the most common cause of death in industrialized society. As the mortality rates from acute myocardial infarction have fallen by more than 50% since the 1970s; coronary artery disease has increasingly become a chronic disease. Outcomes among patients with chronic ischemic heart disease are heterogeneous, with excellent survival in many, while other high-risk subsets are at notably increased risk for death or major complications. Managing the growing population of patients with chronic coronary disease requires understanding of the full clinical spectrum of coronary disease, ranging from patients with advanced, but asymptomatic disease to those with ischemic cardiomyopathy at risk for heart failure and sudden cardiac death. Importantly, in this chronic condition understanding the impact of angina and other symptoms on quality of life and functional status is particularly important. Paralleling the growth in the chronic coronary disease population is the rapid pace of progress with regard to preventive strategies, diagnostic modalities, and new treatment options. In this companion to Braunwald’s Heart Disease we provide comprehensive coverage of chronic coronary artery disease. This text includes 30 chapters that are designed to provide the clinical practitioner and researcher with in depth understanding of factors responsible for disease development, as well as immediately actionable information regarding all available diagnostic and treatment modalities. We have assembled a superb team of international contributors who have provided authoritative coverage of their areas of expertise. The text is divided into four sections, beginning with an introductory section reviewing the epidemiology of chronic coronary artery disease, and providing a global perspective on the disease spectrum. This is followed by sections covering pathogenesis, clinical evaluation, and management. As compared with broad-based cardiovascular textbooks, this focused companion “dives deep” into this important topic area. For example, we include individual chapters on each available testing modality for evaluating coronary disease. These chapters are followed by integrative chapters that provide algorithms to help clinicians select among the various testing options.