Lupus Renal Involvement A Case-based Atlas PDF Free Download
|Author||Natalino Salgado Filho and Stanley De Almeida Araujo|
|File size||3.2 MB|
Systemic lupus erythematosus (SLE or lupus) is a fairly common disease with a relatively high mortality rate that is characterized by multisystemic disorders including the kidney. Recently epidemiologic studies also show that the incidence of new SLE cases is increasing.
Renal involvement is very common in systemic lupus erythematosus occurring in up to 2/3 of patients and is a major cause of morbidity and mortality. Lupus nephritis affects glomeruli tubules interstitium peritubular capillaries arteries and veins with a spectrum of lesion. Although tubular interstitial and vascular lesions are common in lupus nephritis and may contribute significantly to overall disease severity activity and chronicity they are not considered in most important classifications (OMS and ISN/RPS). These classifications are based entirely on the evaluation of glomerular alterations. Furthermore the increasingly recognized new pathological entity called lupus podocitopathy in the context of SLE is not also accepted in the above classifications. Amyloidosis non-lupus nephritides (including IgA nephropathy) therapeutic nephrotoxicity and lupus in overlap with other connective tissue diseases are occasionally described.
Therefore this new case-based book fills a gap in the literature and the authors call attention to some clinical entities which are less known and more difficult to recognize. The book design allows correlating morphologic aspects with clinical findings and determines the prognosis and therapeutic response. It is a useful resource for pathologists nephrologists rheumatologist physicians and lupus and kidney students. Each case consists of typical histology images a brief history diagnosis discussion and pearls and pitfalls. The book is based on a multicenter experience and the importance of kidney biopsy in the differential diagnosis is emphasized. (Imprint: Nova Biomedical)
Lupus Renal Involvement A Case-based Atlas PDF Lupus Renal Involvement A Case-based Atlas PDF Free Download Lupus Renal Involvement A Case-based Atlas PDF Ebook