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This book attempts to summarise the rapid progress that has recently been made in understanding and treating people with VCFS. We hope that publication of this book will be useful for several reasons: (1) professionals studying or treating one aspect of VCFS are often relatively unaware of the involvement of other systems and this book will assist them in obtaining a more holistic view of people with VCFS; (2) VCFS may been seen as a paradigm for other less common microdeletion disorders and experience with VCFS may help to direct research and treatment strategies across a range of other microdeletion disorders; (3) while this book emphasises the clinical issues relevant to VCFS, it also reflects the increasing recognition that an understanding of relatively rare disorders such as VCFS can tell us much about more common conditions, such as predisposition to psychiatric illness; (4) the study of the embryological basis for the structural malformations observed inVCFS is helping to uncover some basic mechanisms of developmental biology. There has recently been considerable excitement at how rapidly our understanding of VCFS has evolved and we have sought to convey this excitement in this book. In addition, we have been privileged to meet numerous people with VCFS and their families over the past decade and have been inspired by the courage and dedication of affected individuals and their families. We dedicate this book to them.
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